test facilities

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Diluted atmosphere exposure system

Rodents exposure to diluted aerosols in physiological conditions is made possible with specific exposure cages. Animals are not anaesthetized and not tied, hence the fonctionnality of cardio-respiratory apparatus is normal.

Internal aerodynamic modelisation (Fluent software)

Exposure cages are constituted of two parts:

A mixing zone room where recirculating events occur
An exposure place where aerosol flow is laminar

An atmosphere dilution and sampling system

C ERTAM have an animal housing facility located just beneath the engine test cells.
Freshly emitted engine exhausts are sampled and diluted to concentrations similar to those observed onboard in vehicles. Then, the aerosol is regulated in relative hygrometry and is leaded trough the exposure cages.

Physiological studies

Day per dayelectrocardiography tracking from each animal before, after and during exposure.
Respiratory physiology evaluation with plethysmography
Cardiac, pulmonary, hepatic and renal toxicity

Contact: david.preterre@certam-rouen.com